燕达国际医院消化科
郑日男
内镜在消化系疾病诊治中的应用
内镜发展史
1806-硬式内镜
---德国法兰克福,Bozzin
1957-纤维内镜
---美国医生,Hirschowitz
1983-电子胃镜
---美国,Welch Allyn公司
---电视监视器
Chromoendoscopy
Magnifying endoscopy
IPCL
NBI, AFI
EMR
ESD
ERCP
EUS
NOTES
Esophageal anatomy
Ce: cervical
esophaguse
Ut: upper thoracic esophagus
Mt: middle thoracic
esophagus
Lt: lower thoracic esophagus
Ae:Abdominal esophagus
Epithelium
Lamina prop.
Mascularis
mucosae
Submucosa
Prop. muscle
Serosa
m1
m2
m3
sm1
sm2
sm3
Depth of tumor invasion
正常食管组织病理
Epithelium
Lamina propria
Muscularis mucosae
Circular muscle
Longitudinal muscle
Submucosa
Serosa
Epidemiology of the esophageal cancer
Carcinoma of the esophagus incidence
North china 130/100,000 population
America 5/100,000 population
Japan 5/100,000 population
Urban China
Rural China
United States
United Kingdom
Switzerland
(2001)
0
5
10
15
20
25
30
35
40
45
50
55
(2000)
(1999)
(1999)
(1999)
(1999)
(1998)
(1999)
(1999)
(1999)
(1999)
(1999)
(2000)
(1997)
(1999)
Mortality per 100,000 males
Japan
Korea
Italy
Canada
Germany
France
Sweden
Australia
Russia
Argentina
Country
Hatakeyama et al. nature acer 2004 Sep;4(9):688-94
食管癌的病理
(病変部位)
日本
Mt: %
Lt: %
Ut: %
中国
Mt:-%
Lt:-%
Ut:-%